All you need to know ahead of Saturday's game
Whilst The Lions are sitting joint seventh with Sheffield United on 40 points, one off sixth-placed Peterborough United, Chesterfield's mini revival under Wilson's managership has seen them climb four points clear of the drop zone in 18th place, although the Spireites have played at least one game more than five of the six teams currently beneath them in the table.
Wilson, who was confirmed as Dean Saunders' successor on Christmas Eve, officially took charge of his first game in the Chesterfield hot-seat on 28th December - a 1-1 draw with promotion-chasing Coventry City. This was followed by a sensational 7-1 drubbing of Shrewsbury Town and 3-2 success over Rochdale, before slipping up at Wigan.
However, The Lions come up against a Spireites side who are determined to bounce back to winning ways after suffering the first League defeat of new manager Danny Wilson's tenure last weekend, a 3-1 reverse at Wigan Athletic.
The quality of Millwall's attacking play in a dazzling first-half during which they scored three goals was up there with the best produced all season and showed just what Harris' men are capable of when everything clicks into gear.
Neil Harris' Lions head to the Proact Stadium for the first time ever in optimistic mood having moved to within one point of the Play-Offs with last Sunday's 3-1 home win over Port Vale.
Millwall head to Chesterfield on Saturday aiming to make it four wins from their last five Sky Bet League One matches - and at the same time keep the pressure on the top six.
What the managers say
Neil Harris: "Danny has gone in there and made a real impact, as you would expect from a senior manager. His record speaks for itself so I've got a lot of respect for him. We want to keep improving all the time and winning games gives you confidence. We are coming off the back of a win in the League and we go to Chesterfield really thoughtful towards the opposition, meticulous in our preparation but also focused on us and how we can create chances and score goals."
Danny Wilson: "The lads are all looking forward to this weekend. I was disappointed with our first 45 minutes at Wigan last time, but the second half saw some good performances from us; you can't question the players and their work ethic. Sometimes you just have to work a bit smarter though and at times we didn't, we got caught making decisions too late or were in too much of a rush and then picked off with balls behind us. Sometimes you've got to think on your feet . It's important they understand to understand our game plan."
Chesterfield manager Danny Wilson has no fresh injuries to contend with following the Spireites' 3-1 defeat at Wigan Athletic.
Wilson will be able to call on the services of tricky winger Gboly Ariyibi, who has served a one-match ban after picking up two yellow cards for simulation.
Ariyibi looks set to return, with Dan Gardner the player most likely to give way. Drew Talbot could also be pushing for a first-team start, possibly at left-back, where midfielder Dion Donohue has recently stepped in to fill the gap.
Ian Evatt (achilles) remains sidelined for around another two weeks.
Lions boss Neil Harris is playing his cards close to his chest following Sunday's 3-1 home success against Port Vale, but looks unlikely to tinker with his starting line-up too much at the Proact Stadium this weekend.
The likes of John Marquis, Fred Onyedinma, Sid Nelson and Ben Thompson - all vying for a place in Saturday's squad - maintained their match fitness levels too, with a good workout for Justin Skinner's U21s in Monday's 1-1 draw at Charlton.
Carlos Edwards (hamstring) and Tony Craig (knee) remain sidelined.
The Spireites and Lions have met on 36 previous occasions and there is next to nothing to separate the two teams with Millwall holding a narrow 15-14 win advantage in all competitions. The remaining seven matches have finished all square.
Millwall aim to buck a rather strange trend that has seen 11 of Chesterfield's 14 victories against The Lions coming on their own turf.
Neil Harris' charges will be hoping to ensure that there is a shift in home comfort now that The Spireites have moved from Saltergate to their new Proact Stadium and, as they did at Shrewsbury's Greenhous Stadium on the opening day of the season, mark a first ever visit to Chesterfield's new ground with a win.
Last time we met
Two goals from Chesterfield's Jay O'Shea secured a 2-0 victory when the sides last locked horns at The Den on Saturday 29th August 2015.
Whilst O'Shea's 17th-minute opener was a goal good enough to grace any stage, a wonderful first-time volley, his second in the dying seconds of the game took a huge deflection on its way past the wrong-footed Jordan Archer.
Millwall: Archer, Cummings (Marquis, 86mins), Beevers, Nelson, Craig, Onyedinma, Abdou, Powell (Cowan-Hall, 76mins), Thompson, Gregory (O'Brien, 46mins), Morison. Subs not used: Forde, Williams, Upson, Webster.
Chesterfield: Lee, Morsy, Hird, Evatt, Jones, Gardner (Raglan, 87mins), Martinez, O'Neil, Ariyibi (Dieseruvwe, 72mins), Ebanks-Blake (Gnanduillet, 72mins), O'Shea. Subs not used: Humphreys, Harrison, Banks, Cairns
Full match audio commentary will be broadcast on Lions PlayerHD. For details of how to tune in, please click here.
Regular updates, as ever, will also be posted via @MillwallFC
, the club's official Twitter account.
Millwall are 13/10 with Sky Bet
for victory at Chesterfield on Saturday. The hosts are 2/1 and the draw can be found at 12/5.
Lee Gregory, who bagged a brace last time out against Port Vale, is 11/2 to score first and an inviting 11/1 with Sky Bet
to repeat his two-goal haul once more.
Tweets by @MillwallFC
Steve Morison is priced 11/2 to score first or last, whilst latest loan signing Jed Wallace can be found at 17/2 to open or close the scoring at the Proact Stadium.