Lions boss Kenny Jackett could hand three players - four including Tony Craig - their League One debuts in Saturday's opener at Oldham Athletic.
Summer signings David Forde, Jimmy Abdou (below) and striker Tresor Kandol, who agreed a six-month loan from Leeds on Thursday, are all in line for a place in Millwall's starting XI at Boundary Park.
Left-back Tony, who re-joined Millwall from Crystal Palace during the close season, is in line for his third 'official' debut for the club.
Tony made his first senior start when Mark McGhee was manager, before making his 'second' whilst on loan at The Den from Palace in the latter stages of last season.
Having featured prominantly throughout pre-season, he is vying with Andy Frampton to fill the left-back berth at Oldham to complete a hat-trick of debuts!
A 17-man Lions squad set off on the journey up north on Friday morning, with a training session at Liverpool's Youth Academy ground scheduled for the afternoon.
The travelling squad is as follows: Forde, Edwards, Dunne, Craig, Frampton, Robinson, Whitbread, Hackett, Martin, Abdou, Spiller, Fuseini, Laird, Brkovic, Alexander, Grabban, Kandol.
Meanwhile Oldham will be unable to call on the services of experienced striker Lee Hughes who is ruled out with a fractured toe.
Latics expect to hand former Southend United midfielder Kevin Maher his debut, with fellow new signings Kieran Lee, Chris O'Grady, Danny Whitaker and David Williams also hoping to get their first League One outings for the club.